She was born to Francis Calyxtus O'Keeffe and Ida Totto O'Keeffe on a large dairy farm in Wisconsin. She was an American painter, trained in Chicago and New York where she came into contact with modern developments in art, as well as non-western traditions and photography. Her husband, the photographer Alfred Steiglitz showed her work yearly until his death in 1946. O'Keeffe is best known for extreme close-up images of abstracted natural forms, such as flowers, animal bones, clouds, and landscapes. From 1929 she spent most of her summers painting in New Mexico, moving there permanently in 1949. In 1971, she learned to be a hand-potter.